Buffalo Bills 2025 schedule and complete game calendar
The 2025 NFL season is here. Take a look or download the complete calendar for Buffalo Bills game schedule in 2025
Showing 16 of 16 games
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Buffalo Bills | Date & Time↑Sorted ascending | Opponent | LocationNot sorted | VenueNot sorted | Score | Shop Teams | |
|---|---|---|---|---|---|---|---|
Buffalo Bills | Sep 7, 2025 Sunday 8:20 PM EDT |  | Home | Highmark Stadium, Orchard Park | - : - | ||
 | Sep 14, 2025 Sunday 1:00 PM EDT | Buffalo Bills | Away | MetLife Stadium, East Rutherford | - : - | ||
Buffalo Bills | Sep 18, 2025 Thursday 8:15 PM EDT |  | Home | Highmark Stadium, Orchard Park | - : - | ||
Buffalo Bills | Sep 28, 2025 Sunday 1:00 PM EDT |  | Home | Highmark Stadium, Orchard Park | - : - | ||
Buffalo Bills | Oct 5, 2025 Sunday 8:20 PM EDT |  | Home | Highmark Stadium, Orchard Park | - : - | ||
 | Oct 13, 2025 Monday 7:15 PM EDT | Buffalo Bills | Away | Mercedes-Benz Stadium, Atlanta | - : - | ||
 | Oct 26, 2025 Sunday 1:00 PM EDT | Buffalo Bills | Away | Bank of America Stadium, Charlotte | - : - | ||
Buffalo Bills | Nov 2, 2025 Sunday 4:25 PM EST |  | Home | Highmark Stadium, Orchard Park | - : - | ||
| Nov 9, 2025 Sunday 1:00 PM EST | Buffalo Bills | Away | Hard Rock Stadium, Opa Locka | - : - | ||
Buffalo Bills | Nov 16, 2025 Sunday 1:00 PM EST |  | Home | Highmark Stadium, Orchard Park | - : - | ||
 | Nov 20, 2025 Thursday 8:15 PM EST | Buffalo Bills | Away | NRG Stadium, Houston | - : - | ||
 | Nov 30, 2025 Sunday 4:25 PM EST | Buffalo Bills | Away | Acrisure Stadium, Pittsburgh | - : - | ||
Buffalo Bills | Dec 7, 2025 Sunday 4:25 PM EST |  | Home | Highmark Stadium, Orchard Park | - : - | ||
| Dec 14, 2025 Sunday 1:00 PM EST | Buffalo Bills | Away | Gillette Stadium, Foxborough | - : - | ||
 | Dec 21, 2025 Sunday 1:00 PM EST | Buffalo Bills | Away | Huntington Bank Field, Cleveland | - : - | ||
Buffalo Bills | Dec 28, 2025 Sunday 4:25 PM EST |  | Home | Highmark Stadium, Orchard Park | - : - |
VENUE
Highmark Stadium, Orchard Park
VENUE
Highmark Stadium, Orchard Park
VENUE
Bank of America Stadium, Charlotte
VENUE
Highmark Stadium, Orchard Park
VENUE
Highmark Stadium, Orchard Park
VENUE
Acrisure Stadium, Pittsburgh
VENUE
Highmark Stadium, Orchard Park
VENUE
Gillette Stadium, Foxborough
VENUE
Huntington Bank Field, Cleveland
VENUE
Highmark Stadium, Orchard Park
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