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MLB Head-to-Head
Chicago White Sox

Chicago White Sox

VS

11 - 18
St Louis Cardinals

St Louis Cardinals

Chicago White Sox vs St Louis Cardinals

Head-to-Head History (2012–2026)

29

Total Games

11

Sox Wins

18

Cardinals Wins

0

Draws

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All Matchups (29)

Sun, Sep 13, 2026
MLB Regular Season
Chicago White Sox @ St Louis Cardinals
1 - 3
Busch Stadium, St. Louis, MO | Chicago Sports Network
Sat, Sep 12, 2026
MLB Regular Season
Chicago White Sox @ St Louis Cardinals
6 - 5
Busch Stadium, St. Louis, MO | Chicago Sports Network
Fri, Sep 11, 2026
MLB Regular Season
Chicago White Sox @ St Louis Cardinals
3 - 7
Busch Stadium, St. Louis, MO | Chicago Sports Network
Thu, Jun 19, 2025
MLB Regular Season
St Louis Cardinals @ Chicago White Sox
5 - 4
Rate Field, Chicago, IL | Chicago Sports Network
Thu, Jun 19, 2025
MLB Regular Season
St Louis Cardinals @ Chicago White Sox
8 - 6
Rate Field, Chicago, IL | Chicago Sports Network
Tue, Jun 17, 2025
MLB Regular Season
St Louis Cardinals @ Chicago White Sox
12 - 2
Rate Field, Chicago, IL | Chicago Sports Network
Sun, May 5, 2024
MLB Regular Season
Chicago White Sox @ St Louis Cardinals
5 - 1
Busch Stadium, St. Louis, MO | NBCSCH
Sat, May 4, 2024
MLB Regular Season
Chicago White Sox @ St Louis Cardinals
6 - 5
Busch Stadium, St. Louis, MO | NBCSCH
Fri, May 3, 2024
MLB Regular Season
Chicago White Sox @ St Louis Cardinals
0 - 3
Busch Stadium, St. Louis, MO | NBCSCH
Sun, Jul 9, 2023
MLB Regular Season
St Louis Cardinals @ Chicago White Sox
4 - 3
Guaranteed Rate Field, Chicago, IL | NBCSCH
Sat, Jul 8, 2023
MLB Regular Season
St Louis Cardinals @ Chicago White Sox
3 - 0
Guaranteed Rate Field, Chicago, IL | NBCSCH
Fri, Jul 7, 2023
MLB Regular Season
St Louis Cardinals @ Chicago White Sox
7 - 8
Guaranteed Rate Field, Chicago, IL | NBCSCH
Wed, May 26, 2021
MLB Regular Season
St Louis Cardinals @ Chicago White Sox
4 - 0
Guaranteed Rate Field, Chicago, IL | MLBN (out-of-market only), NBCSCH
Tue, May 25, 2021
MLB Regular Season
St Louis Cardinals @ Chicago White Sox
3 - 8
Guaranteed Rate Field, Chicago, IL | NBCSCH
Mon, May 24, 2021
MLB Regular Season
St Louis Cardinals @ Chicago White Sox
1 - 5
Guaranteed Rate Field, Chicago, IL | ESPN/ESPN App, NBCSCH
Sun, Aug 16, 2020
MLB Regular Season
St Louis Cardinals @ Chicago White Sox
2 - 7
Guaranteed Rate Field, Chicago, IL | NBCSCH
Sat, Aug 15, 2020
MLB Regular Season
St Louis Cardinals @ Chicago White Sox
5 - 1
Guaranteed Rate Field, Chicago, IL | MLBN (out-of-market only), NBCSCH
Sat, Aug 15, 2020
MLB Regular Season
St Louis Cardinals @ Chicago White Sox
6 - 3
Guaranteed Rate Field, Chicago, IL | NBCSCH
Wed, Jul 11, 2018
MLB Regular Season
St Louis Cardinals @ Chicago White Sox
0 - 4
Guaranteed Rate Field, Chicago, IL | NBCSCH
Tue, Jul 10, 2018
MLB Regular Season
St Louis Cardinals @ Chicago White Sox
14 - 2
Guaranteed Rate Field, Chicago, IL | WGN
Wed, May 2, 2018
MLB Regular Season
Chicago White Sox @ St Louis Cardinals
2 - 3
Busch Stadium, St. Louis, MO | WGN
Tue, May 1, 2018
MLB Regular Season
Chicago White Sox @ St Louis Cardinals
2 - 3
Busch Stadium, St. Louis, MO | NBCSCH
Wed, Jul 22, 2015
MLB Regular Season
St Louis Cardinals @ Chicago White Sox
3 - 2
U.S. Cellular Field, Chicago, IL | NBCSP
Tue, Jul 21, 2015
MLB Regular Season
St Louis Cardinals @ Chicago White Sox
8 - 5
U.S. Cellular Field, Chicago, IL | WPWR
Wed, Jul 1, 2015
MLB Regular Season
Chicago White Sox @ St Louis Cardinals
7 - 1
Busch Stadium, St. Louis, MO | NBCSP
Tue, Jun 30, 2015
MLB Regular Season
Chicago White Sox @ St Louis Cardinals
2 - 1
Busch Stadium, St. Louis, MO | WPWR
Thu, Jun 14, 2012
MLB Regular Season
Chicago White Sox @ St Louis Cardinals
3 - 5
Busch Stadium, St. Louis, MO | MLBN, NBCSP
Wed, Jun 13, 2012
MLB Regular Season
Chicago White Sox @ St Louis Cardinals
0 - 1
Busch Stadium, St. Louis, MO | NBCSP
Tue, Jun 12, 2012
MLB Regular Season
Chicago White Sox @ St Louis Cardinals
6 - 1
Busch Stadium, St. Louis, MO | WCIU

The Chicago White Sox and St Louis Cardinals have faced each other 29 times in the MLB. The all-time series record is 11-18. View the complete head-to-head matchup history between these two MLB teams.

Series records

Decided meetings only, 2012–2026. Every number is from the games listed above.

Longest Chicago White Sox run
3 straight · Aug 16, 2020 – May 25, 2021
Longest St Louis Cardinals run
5 straight · Jul 21, 2015 – Jul 10, 2018
Biggest Chicago White Sox win
7-1 · Jul 1, 2015
Biggest St Louis Cardinals win
14-2 · Jul 10, 2018
Chicago White Sox Schedule St Louis Cardinals Schedule All MLB Teams
Today's Games