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MLB Head-to-Head
San Diego Padres

San Diego Padres

VS

50 - 58
St Louis Cardinals

St Louis Cardinals

San Diego Padres vs St Louis Cardinals

Head-to-Head History (2010–2026)

108

Total Games

50

Padres Wins

58

Cardinals Wins

0

Draws

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47 MLB Team Color Primary Logo MVP Adjustable Hat, Adult One Size Fits All - San Diego Padres - Brown
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All Matchups (108)

Wed, Jun 17, 2026
MLB Regular Season
San Diego Padres @ St Louis Cardinals
6 - 1
Busch Stadium, St. Louis, MO | Padres.TV Presented by UC San Diego Health
Tue, Jun 16, 2026
MLB Regular Season
San Diego Padres @ St Louis Cardinals
2 - 3
Busch Stadium, St. Louis, MO | TBS, TBS (out-of-market only), Padres.TV Presented by UC San Diego Health
Mon, Jun 15, 2026
MLB Regular Season
San Diego Padres @ St Louis Cardinals
0 - 3
Busch Stadium, St. Louis, MO | Padres.TV Presented by UC San Diego Health
Sun, May 10, 2026
MLB Regular Season
St Louis Cardinals @ San Diego Padres
2 - 3
Petco Park, San Diego, CA | Padres.TV Presented by UC San Diego Health
Sat, May 9, 2026
MLB Regular Season
St Louis Cardinals @ San Diego Padres
2 - 4
Petco Park, San Diego, CA | FOX / FOX ONE
Fri, May 8, 2026
MLB Regular Season
St Louis Cardinals @ San Diego Padres
6 - 0
Petco Park, San Diego, CA | Apple TV
Thu, May 7, 2026
MLB Regular Season
St Louis Cardinals @ San Diego Padres
2 - 1
Petco Park, San Diego, CA | ESPN/ESPN App
Sun, Aug 3, 2025
MLB Regular Season
St Louis Cardinals @ San Diego Padres
3 - 7
Petco Park, San Diego, CA | Padres.TV Presented by UC San Diego Health
Sat, Aug 2, 2025
MLB Regular Season
St Louis Cardinals @ San Diego Padres
8 - 5
Petco Park, San Diego, CA | Padres.TV Presented by UC San Diego Health, KFMB 8.2 (CW)
Fri, Aug 1, 2025
MLB Regular Season
St Louis Cardinals @ San Diego Padres
1 - 4
Petco Park, San Diego, CA | Padres.TV Presented by UC San Diego Health
Sun, Jul 27, 2025
MLB Regular Season
San Diego Padres @ St Louis Cardinals
9 - 2
Busch Stadium, St. Louis, MO | Padres.TV Presented by UC San Diego Health
Sat, Jul 26, 2025
MLB Regular Season
San Diego Padres @ St Louis Cardinals
3 - 1
Busch Stadium, St. Louis, MO | Padres.TV Presented by UC San Diego Health, KFMB 8.1 (CBS)
Fri, Jul 25, 2025
MLB Regular Season
San Diego Padres @ St Louis Cardinals
0 - 3
Busch Stadium, St. Louis, MO | Padres.TV Presented by UC San Diego Health
Thu, Jul 24, 2025
MLB Regular Season
San Diego Padres @ St Louis Cardinals
7 - 9
Busch Stadium, St. Louis, MO | Padres.TV Presented by UC San Diego Health
Thu, Aug 29, 2024
MLB Regular Season
San Diego Padres @ St Louis Cardinals
1 - 4
Busch Stadium, St. Louis, MO | Padres.TV Presented by UC San Diego Health
Wed, Aug 28, 2024
MLB Regular Season
San Diego Padres @ St Louis Cardinals
3 - 4
Busch Stadium, St. Louis, MO | Padres.TV Presented by UC San Diego Health
Tue, Aug 27, 2024
MLB Regular Season
San Diego Padres @ St Louis Cardinals
7 - 5
Busch Stadium, St. Louis, MO | Padres.TV Presented by UC San Diego Health
Mon, Aug 26, 2024
MLB Regular Season
San Diego Padres @ St Louis Cardinals
7 - 4
Busch Stadium, St. Louis, MO | Padres.TV Presented by UC San Diego Health
Wed, Apr 3, 2024
MLB Regular Season
St Louis Cardinals @ San Diego Padres
2 - 3
Petco Park, San Diego, CA | MLBN (out-of-market only), Padres.TV Presented by UC San Diego Health
Tue, Apr 2, 2024
MLB Regular Season
St Louis Cardinals @ San Diego Padres
5 - 2
Petco Park, San Diego, CA | Padres.TV Presented by UC San Diego Health
Mon, Apr 1, 2024
MLB Regular Season
St Louis Cardinals @ San Diego Padres
6 - 2
Petco Park, San Diego, CA | Padres.TV Presented by UC San Diego Health
Sun, Sep 24, 2023
MLB Regular Season
St Louis Cardinals @ San Diego Padres
2 - 12
Petco Park, San Diego, CA | MLBN (out-of-market only), Padres.TV Presented by UC San Diego Health
Sat, Sep 23, 2023
MLB Regular Season
St Louis Cardinals @ San Diego Padres
5 - 2
Petco Park, San Diego, CA | Padres.TV Presented by UC San Diego Health
Fri, Sep 22, 2023
MLB Regular Season
St Louis Cardinals @ San Diego Padres
2 - 4
Petco Park, San Diego, CA | MLBN (out-of-market only), Padres.TV Presented by UC San Diego Health
Wed, Aug 30, 2023
MLB Regular Season
San Diego Padres @ St Louis Cardinals
4 - 5
Busch Stadium, St. Louis, MO | Padres.TV Presented by UC San Diego Health
Tue, Aug 29, 2023
MLB Regular Season
San Diego Padres @ St Louis Cardinals
5 - 6
Busch Stadium, St. Louis, MO | Padres.TV Presented by UC San Diego Health
Mon, Aug 28, 2023
MLB Regular Season
San Diego Padres @ St Louis Cardinals
4 - 1
Busch Stadium, St. Louis, MO | Padres.TV Presented by UC San Diego Health
Thu, Sep 22, 2022
MLB Regular Season
St Louis Cardinals @ San Diego Padres
5 - 4
Petco Park, San Diego, CA | Bally Sports San Diego
Wed, Sep 21, 2022
MLB Regular Season
St Louis Cardinals @ San Diego Padres
0 - 1
Petco Park, San Diego, CA | MLBN (out-of-market only), Bally Sports San Diego
Tue, Sep 20, 2022
MLB Regular Season
St Louis Cardinals @ San Diego Padres
0 - 5
Petco Park, San Diego, CA | TBS (out-of-market only), Bally Sports San Diego
Wed, Jun 1, 2022
MLB Regular Season
San Diego Padres @ St Louis Cardinals
2 - 5
Busch Stadium, St. Louis, MO | MLBN (out-of-market only), Bally Sports San Diego
Tue, May 31, 2022
MLB Regular Season
San Diego Padres @ St Louis Cardinals
2 - 3
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Mon, May 30, 2022
MLB Regular Season
San Diego Padres @ St Louis Cardinals
3 - 6
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Sun, Sep 19, 2021
MLB Regular Season
San Diego Padres @ St Louis Cardinals
7 - 8
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Sat, Sep 18, 2021
MLB Regular Season
San Diego Padres @ St Louis Cardinals
2 - 3
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Fri, Sep 17, 2021
MLB Regular Season
San Diego Padres @ St Louis Cardinals
2 - 8
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Sun, May 16, 2021
MLB Regular Season
St Louis Cardinals @ San Diego Padres
3 - 5
Petco Park, San Diego, CA | ESPN/ESPN App
Sat, May 15, 2021
MLB Regular Season
St Louis Cardinals @ San Diego Padres
3 - 13
Petco Park, San Diego, CA | FS1
Fri, May 14, 2021
MLB Regular Season
St Louis Cardinals @ San Diego Padres
4 - 5
Petco Park, San Diego, CA | Bally Sports San Diego
Fri, Oct 2, 2020
NL Wild Card Series
St Louis Cardinals @ San Diego Padres
0 - 4
Petco Park, San Diego, CA | ESPN/ESPN App
Thu, Oct 1, 2020
NL Wild Card Series
St Louis Cardinals @ San Diego Padres
9 - 11
Petco Park, San Diego, CA | ESPN/ESPN App
Wed, Sep 30, 2020
NL Wild Card Series
St Louis Cardinals @ San Diego Padres
7 - 4
Petco Park, San Diego, CA | ESPN2
Sun, Jun 30, 2019
MLB Regular Season
St Louis Cardinals @ San Diego Padres
5 - 3
Petco Park, San Diego, CA | Bally Sports San Diego
Sat, Jun 29, 2019
MLB Regular Season
St Louis Cardinals @ San Diego Padres
2 - 12
Petco Park, San Diego, CA | Bally Sports San Diego
Fri, Jun 28, 2019
MLB Regular Season
St Louis Cardinals @ San Diego Padres
1 - 3
Petco Park, San Diego, CA | Bally Sports San Diego
Sun, Apr 7, 2019
MLB Regular Season
San Diego Padres @ St Louis Cardinals
1 - 4
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Sat, Apr 6, 2019
MLB Regular Season
San Diego Padres @ St Louis Cardinals
6 - 4
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Fri, Apr 5, 2019
MLB Regular Season
San Diego Padres @ St Louis Cardinals
5 - 3
Busch Stadium, St. Louis, MO | MLBN (out-of-market only), Bally Sports San Diego
Wed, Jun 13, 2018
MLB Regular Season
San Diego Padres @ St Louis Cardinals
4 - 2
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Tue, Jun 12, 2018
MLB Regular Season
San Diego Padres @ St Louis Cardinals
4 - 2
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Mon, Jun 11, 2018
MLB Regular Season
San Diego Padres @ St Louis Cardinals
2 - 5
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Sun, May 13, 2018
MLB Regular Season
St Louis Cardinals @ San Diego Padres
3 - 5
Petco Park, San Diego, CA | Bally Sports San Diego
Sat, May 12, 2018
MLB Regular Season
St Louis Cardinals @ San Diego Padres
1 - 2
Petco Park, San Diego, CA | Bally Sports San Diego
Fri, May 11, 2018
MLB Regular Season
St Louis Cardinals @ San Diego Padres
9 - 5
Petco Park, San Diego, CA | Bally Sports San Diego
Thu, May 10, 2018
MLB Regular Season
St Louis Cardinals @ San Diego Padres
2 - 1
Petco Park, San Diego, CA | Bally Sports San Diego
Thu, Sep 7, 2017
MLB Regular Season
St Louis Cardinals @ San Diego Padres
0 - 3
Petco Park, San Diego, CA | Bally Sports San Diego
Wed, Sep 6, 2017
MLB Regular Season
St Louis Cardinals @ San Diego Padres
3 - 1
Petco Park, San Diego, CA | Bally Sports San Diego
Tue, Sep 5, 2017
MLB Regular Season
St Louis Cardinals @ San Diego Padres
8 - 4
Petco Park, San Diego, CA | Bally Sports San Diego
Mon, Sep 4, 2017
MLB Regular Season
St Louis Cardinals @ San Diego Padres
2 - 0
Petco Park, San Diego, CA | Bally Sports San Diego
Thu, Aug 24, 2017
MLB Regular Season
San Diego Padres @ St Louis Cardinals
4 - 3
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Wed, Aug 23, 2017
MLB Regular Season
San Diego Padres @ St Louis Cardinals
2 - 6
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Tue, Aug 22, 2017
MLB Regular Season
San Diego Padres @ St Louis Cardinals
12 - 4
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Thu, Jul 21, 2016
MLB Regular Season
San Diego Padres @ St Louis Cardinals
5 - 6
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Wed, Jul 20, 2016
MLB Regular Season
San Diego Padres @ St Louis Cardinals
2 - 4
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Wed, Jul 20, 2016
MLB Regular Season
San Diego Padres @ St Louis Cardinals
2 - 3
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Mon, Jul 18, 2016
MLB Regular Season
San Diego Padres @ St Louis Cardinals
2 - 10
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Sun, Apr 24, 2016
MLB Regular Season
St Louis Cardinals @ San Diego Padres
8 - 5
Petco Park, San Diego, CA | Bally Sports San Diego
Sat, Apr 23, 2016
MLB Regular Season
St Louis Cardinals @ San Diego Padres
11 - 2
Petco Park, San Diego, CA | Bally Sports San Diego
Fri, Apr 22, 2016
MLB Regular Season
St Louis Cardinals @ San Diego Padres
1 - 4
Petco Park, San Diego, CA | Bally Sports San Diego
Sun, Aug 23, 2015
MLB Regular Season
St Louis Cardinals @ San Diego Padres
10 - 3
Petco Park, San Diego, CA | Bally Sports San Diego, Bally Deportes San Diego
Sat, Aug 22, 2015
MLB Regular Season
St Louis Cardinals @ San Diego Padres
0 - 8
Petco Park, San Diego, CA | Bally Sports San Diego, Bally Deportes San Diego
Fri, Aug 21, 2015
MLB Regular Season
St Louis Cardinals @ San Diego Padres
3 - 9
Petco Park, San Diego, CA | Bally Sports San Diego, Bally Deportes San Diego
Sun, Jul 5, 2015
MLB Regular Season
San Diego Padres @ St Louis Cardinals
1 - 3
Busch Stadium, St. Louis, MO | Bally Sports San Diego, Bally Deportes San Diego
Sat, Jul 4, 2015
MLB Regular Season
San Diego Padres @ St Louis Cardinals
1 - 2
Busch Stadium, St. Louis, MO | Bally Sports San Diego, Bally Deportes San Diego
Fri, Jul 3, 2015
MLB Regular Season
San Diego Padres @ St Louis Cardinals
2 - 1
Busch Stadium, St. Louis, MO | Bally Sports San Diego, Bally Deportes San Diego
Thu, Jul 2, 2015
MLB Regular Season
San Diego Padres @ St Louis Cardinals
5 - 3
Busch Stadium, St. Louis, MO | MLBN, Bally Sports San Diego, Bally Deportes San Diego
Sun, Aug 17, 2014
MLB Regular Season
San Diego Padres @ St Louis Cardinals
6 - 7
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Sat, Aug 16, 2014
MLB Regular Season
San Diego Padres @ St Louis Cardinals
9 - 5
Busch Stadium, St. Louis, MO | FS1
Fri, Aug 15, 2014
MLB Regular Season
San Diego Padres @ St Louis Cardinals
2 - 4
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Thu, Aug 14, 2014
MLB Regular Season
San Diego Padres @ St Louis Cardinals
3 - 4
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Thu, Jul 31, 2014
MLB Regular Season
St Louis Cardinals @ San Diego Padres
6 - 2
Petco Park, San Diego, CA | Bally Sports San Diego
Wed, Jul 30, 2014
MLB Regular Season
St Louis Cardinals @ San Diego Padres
1 - 12
Petco Park, San Diego, CA | Bally Sports San Diego
Tue, Jul 29, 2014
MLB Regular Season
St Louis Cardinals @ San Diego Padres
1 - 3
Petco Park, San Diego, CA | Bally Sports San Diego
Sun, Jul 21, 2013
MLB Regular Season
San Diego Padres @ St Louis Cardinals
2 - 3
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Sat, Jul 20, 2013
MLB Regular Season
San Diego Padres @ St Louis Cardinals
5 - 3
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Fri, Jul 19, 2013
MLB Regular Season
San Diego Padres @ St Louis Cardinals
6 - 9
Busch Stadium, St. Louis, MO | Bally Sports San Diego
Wed, May 22, 2013
MLB Regular Season
St Louis Cardinals @ San Diego Padres
5 - 3
Petco Park, San Diego, CA | Bally Sports San Diego
Tue, May 21, 2013
MLB Regular Season
St Louis Cardinals @ San Diego Padres
10 - 2
Petco Park, San Diego, CA | Bally Sports San Diego
Mon, May 20, 2013
MLB Regular Season
St Louis Cardinals @ San Diego Padres
2 - 4
Petco Park, San Diego, CA | Bally Sports San Diego
Wed, Sep 12, 2012
MLB Regular Season
St Louis Cardinals @ San Diego Padres
2 - 3
Petco Park, San Diego, CA
Tue, Sep 11, 2012
MLB Regular Season
St Louis Cardinals @ San Diego Padres
4 - 6
Petco Park, San Diego, CA
Mon, Sep 10, 2012
MLB Regular Season
St Louis Cardinals @ San Diego Padres
3 - 11
Petco Park, San Diego, CA
Wed, May 23, 2012
MLB Regular Season
San Diego Padres @ St Louis Cardinals
3 - 6
Busch Stadium, St. Louis, MO
Tue, May 22, 2012
MLB Regular Season
San Diego Padres @ St Louis Cardinals
0 - 4
Busch Stadium, St. Louis, MO
Mon, May 21, 2012
MLB Regular Season
San Diego Padres @ St Louis Cardinals
3 - 4
Busch Stadium, St. Louis, MO
Wed, May 25, 2011
MLB Regular Season
St Louis Cardinals @ San Diego Padres
1 - 3
PETCO Park, San Diego, CA
Tue, May 24, 2011
MLB Regular Season
St Louis Cardinals @ San Diego Padres
3 - 2
PETCO Park, San Diego, CA | MLBN, 4 San Diego
Mon, May 23, 2011
MLB Regular Season
St Louis Cardinals @ San Diego Padres
3 - 1
PETCO Park, San Diego, CA | 4 San Diego
Sun, Apr 3, 2011
MLB Regular Season
San Diego Padres @ St Louis Cardinals
0 - 2
Busch Stadium, St. Louis, MO | 4 San Diego
Sat, Apr 2, 2011
MLB Regular Season
San Diego Padres @ St Louis Cardinals
11 - 3
Busch Stadium, St. Louis, MO | FOX
Thu, Mar 31, 2011
MLB Regular Season
San Diego Padres @ St Louis Cardinals
5 - 3
Busch Stadium, St. Louis, MO | ESPN/ESPN App, 4 San Diego
Sun, Sep 19, 2010
MLB Regular Season
San Diego Padres @ St Louis Cardinals
1 - 4
Busch Stadium, St. Louis, MO | 4 San Diego
Sat, Sep 18, 2010
MLB Regular Season
San Diego Padres @ St Louis Cardinals
8 - 4
Busch Stadium, St. Louis, MO | FOX
Fri, Sep 17, 2010
MLB Regular Season
San Diego Padres @ St Louis Cardinals
4 - 14
Busch Stadium, St. Louis, MO | 4 San Diego
Thu, Sep 16, 2010
MLB Regular Season
San Diego Padres @ St Louis Cardinals
0 - 4
Busch Stadium, St. Louis, MO | MLBN, 4 San Diego
Thu, May 27, 2010
MLB Regular Season
St Louis Cardinals @ San Diego Padres
8 - 3
PETCO Park, San Diego, CA
Wed, May 26, 2010
MLB Regular Season
St Louis Cardinals @ San Diego Padres
1 - 2
PETCO Park, San Diego, CA | 4 San Diego
Tue, May 25, 2010
MLB Regular Season
St Louis Cardinals @ San Diego Padres
0 - 1
PETCO Park, San Diego, CA | 4 San Diego

The San Diego Padres and St Louis Cardinals have faced each other 108 times in the MLB. The all-time series record is 50-58. View the complete head-to-head matchup history between these two MLB teams.

Series records

Decided meetings only, 2010–2026. Every number is from the games listed above.

Longest San Diego Padres run
5 straight · Oct 1, 2020 – May 16, 2021
Longest St Louis Cardinals run
6 straight · Apr 23 – Jul 21, 2016
Biggest San Diego Padres win
12-1 · Jul 30, 2014
Biggest St Louis Cardinals win
14-4 · Sep 17, 2010
San Diego Padres Schedule St Louis Cardinals Schedule All MLB Teams
Today's Games