Skip to content
NFL Head-to-Head
Los Angeles Rams

Los Angeles Rams

VS

12 - 1 - 20
San Francisco 49ers

San Francisco 49ers

Los Angeles Rams vs San Francisco 49ers

Head-to-Head History (2010–2026)

33

Total Games

12

Rams Wins

20

49ers Wins

1

Draws

Rep Your Side

As an Amazon Associate we earn from qualifying purchases. Prices checked Sep 10, 2026.

New Era NFL Core Classic 9TWENTY Graphite Adjustable Hat Cap - One Size (US, Alpha, One Size, San Francisco 49ers)
New Era In Stock

New Era NFL Core Classic 9TWENTY Graphite Adjustable Hat Cap - One Size (US, Alpha, One Size, San Francisco 49ers)

$39.99 View on Amazon
New Era NFL The League 9FORTY Adjustable Hat Cap One Size Fits All (San Francisco 49ers Black)
New Era Currently unavailable.

New Era NFL The League 9FORTY Adjustable Hat Cap One Size Fits All (San Francisco 49ers Black)

Check price on Amazon

All Matchups (35)

Sun, Dec 13, 2026 Week 14
Regular Season
Los Angeles Rams @ San Francisco 49ers
Scheduled
Levi's® Stadium, Santa Clara | FOX
Thu, Sep 10, 2026 Week 1
Regular Season
San Francisco 49ers @ Los Angeles Rams
Scheduled
Melbourne Cricket Ground, East Melbourne | NETFLIX
Sun, Nov 9, 2025 Week 10
Regular Season
Los Angeles Rams @ San Francisco 49ers
42 - 26
Levi's® Stadium, Santa Clara | FOX
Thu, Oct 2, 2025 Week 5
Regular Season
San Francisco 49ers @ Los Angeles Rams
26 - 23
SoFi Stadium, Inglewood | Prime Video, PRIME, PRIMESPANISH, PRIMEALT1
Thu, Dec 12, 2024 Week 15
Regular Season
Los Angeles Rams @ San Francisco 49ers
12 - 6
Levi's® Stadium, Santa Clara | Prime Video, PRIME, PRIMESPANISH, PRIMEALT1
Sun, Sep 22, 2024 Week 3
Regular Season
San Francisco 49ers @ Los Angeles Rams
24 - 27
SoFi Stadium, Inglewood | FOX
Sun, Jan 7, 2024 Week 18
Regular Season
Los Angeles Rams @ San Francisco 49ers
21 - 20
Levi's® Stadium, Santa Clara | FOX
Sun, Sep 17, 2023 Week 2
Regular Season
San Francisco 49ers @ Los Angeles Rams
30 - 23
SoFi Stadium, Inglewood | FOX
Sun, Oct 30, 2022 Week 8
Regular Season
San Francisco 49ers @ Los Angeles Rams
31 - 14
SoFi Stadium, Inglewood | FOX
Mon, Oct 3, 2022 Week 4
Regular Season
Los Angeles Rams @ San Francisco 49ers
9 - 24
Levi's® Stadium, Santa Clara | ESPN, ESPN2, ESPN Deportes
Sun, Jan 30, 2022 Week 3
Postseason · Conference Championship
San Francisco 49ers @ Los Angeles Rams
17 - 20
SoFi Stadium, Inglewood | FOX
Sun, Jan 9, 2022 Week 18
Regular Season
San Francisco 49ers @ Los Angeles Rams
27 - 24
SoFi Stadium, Inglewood | FOX
Mon, Nov 15, 2021 Week 10
Regular Season
Los Angeles Rams @ San Francisco 49ers
10 - 31
Levi's® Stadium, Santa Clara | ESPN, ESPN2
Sun, Nov 29, 2020 Week 12
Regular Season
San Francisco 49ers @ Los Angeles Rams
23 - 20
SoFi Stadium, Inglewood | FOX
Sun, Oct 18, 2020 Week 6
Regular Season
Los Angeles Rams @ San Francisco 49ers
16 - 24
Levi's® Stadium, Santa Clara | NBC
Sat, Dec 21, 2019 Week 16
Regular Season
Los Angeles Rams @ San Francisco 49ers
31 - 34
Levi's® Stadium, Santa Clara | NFL NETWORK
Sun, Oct 13, 2019 Week 6
Regular Season
San Francisco 49ers @ Los Angeles Rams
20 - 7
Los Angeles Memorial Coliseum, Los Angeles | FOX
Sun, Dec 30, 2018 Week 17
Regular Season
San Francisco 49ers @ Los Angeles Rams
32 - 48
Los Angeles Memorial Coliseum, Los Angeles | FOX
Sun, Oct 21, 2018 Week 7
Regular Season
Los Angeles Rams @ San Francisco 49ers
39 - 10
Levi's® Stadium, Santa Clara | CBS
Sun, Dec 31, 2017 Week 17
Regular Season
San Francisco 49ers @ Los Angeles Rams
34 - 13
Los Angeles Memorial Coliseum, Los Angeles | FOX
Thu, Sep 21, 2017 Week 3
Regular Season
Los Angeles Rams @ San Francisco 49ers
41 - 39
Levi's® Stadium, Santa Clara | NFL NETWORK
Sat, Dec 24, 2016 Week 16
Regular Season
San Francisco 49ers @ Los Angeles Rams
22 - 21
Los Angeles Memorial Coliseum, Los Angeles | FOX
Mon, Sep 12, 2016 Week 1
Regular Season
Los Angeles Rams @ San Francisco 49ers
0 - 28
Levi's® Stadium, Santa Clara | ESPN
Sun, Jan 3, 2016 Week 17
Regular Season
Los Angeles Rams @ San Francisco 49ers
16 - 19
Levi's® Stadium, Santa Clara | CBS
Sun, Nov 1, 2015 Week 8
Regular Season
San Francisco 49ers @ Los Angeles Rams
6 - 27
Edward Jones Dome, St. Louis | FOX
Sun, Nov 2, 2014 Week 9
Regular Season
Los Angeles Rams @ San Francisco 49ers
13 - 10
Levi's® Stadium, Santa Clara | FOX
Mon, Oct 13, 2014 Week 6
Regular Season
San Francisco 49ers @ Los Angeles Rams
31 - 17
Edward Jones Dome, St. Louis | ESPN
Sun, Dec 1, 2013 Week 13
Regular Season
Los Angeles Rams @ San Francisco 49ers
13 - 23
Candlestick Park, San Francisco | FOX
Thu, Sep 26, 2013 Week 4
Regular Season
San Francisco 49ers @ Los Angeles Rams
35 - 11
Edward Jones Dome, St. Louis | NFL NETWORK
Sun, Dec 2, 2012 Week 13
Regular Season
San Francisco 49ers @ Los Angeles Rams
13 - 16
Edward Jones Dome, St. Louis
Sun, Nov 11, 2012 Week 10
Regular Season
Los Angeles Rams @ San Francisco 49ers
24 - 24
Candlestick Park, San Francisco
Sun, Jan 1, 2012 Week 17
Regular Season
San Francisco 49ers @ Los Angeles Rams
34 - 27
Edward Jones Dome, St. Louis
Sun, Dec 4, 2011 Week 13
Regular Season
Los Angeles Rams @ San Francisco 49ers
0 - 26
Candlestick Park, San Francisco
Sun, Dec 26, 2010 Week 16
Regular Season
San Francisco 49ers @ Los Angeles Rams
17 - 25
Edward Jones Dome, St. Louis
Sun, Nov 14, 2010 Week 10
Regular Season
Los Angeles Rams @ San Francisco 49ers
20 - 23
Candlestick Park, San Francisco

The Los Angeles Rams and San Francisco 49ers have faced each other 35 times in the NFL. The all-time series record is 12-20-1. View the complete head-to-head matchup history between these two NFL teams.

Series records

Decided meetings only, 2010–2025. Every number is from the games listed above.

Longest Los Angeles Rams run
3 straight · Jan 7 – Dec 12, 2024
Longest San Francisco 49ers run
6 straight · Oct 13, 2019 – Jan 9, 2022
Biggest Los Angeles Rams win
39-10 · Oct 21, 2018
Biggest San Francisco 49ers win
28-0 · Sep 12, 2016
Los Angeles Rams Schedule San Francisco 49ers Schedule All NFL Teams
Today's Games