San Francisco 49ers 2021 Schedule & Results
Complete 2021 NFL season schedule, scores, and results for the San Francisco 49ers.
San Francisco 49ers 2021 Schedule & Results
Saturday, August 14, 2021 · Levi's® Stadium
Game Details
- Venue
- Levi's® Stadium
- Location
- Santa Clara
- Time
- 8:30 PM EDT
- Attendance
- 54,397
- Weather
- Clear Temp: 79° F, Humidity: 52%, Wind: NW 12 mph
Score by Quarter
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| Kansas City Chiefs | 7 | 0 | 3 | 9 | 19 |
| San Francisco 49ers | 6 | 3 | 0 | 7 | 16 |
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The San Francisco 49ers hosted the Kansas City Chiefs at Levi's® Stadium in Santa Clara on Saturday, August 14, 2021. The final score was San Francisco 49ers 16, Kansas City Chiefs 19. This was a Preseason Week 1 game.
Sunday, August 22, 2021 · SoFi Stadium
Game Details
- Venue
- SoFi Stadium
- Location
- Inglewood
- Time
- 7:30 PM EDT
- Attendance
- 68,327
- Weather
- Clear Temp: 73° F, Humidity: 60%, Wind: WSW 15 mph
Score by Quarter
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| San Francisco 49ers | 0 | 8 | 7 | 0 | 15 |
| Los Angeles Chargers | 0 | 10 | 0 | 0 | 10 |
Broadcast
- Local TV:
- NFL NETWORK
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The Los Angeles Chargers hosted the San Francisco 49ers at SoFi Stadium in Inglewood on Sunday, August 22, 2021. The final score was Los Angeles Chargers 10, San Francisco 49ers 15. This was a Preseason Week 2 game. The game was broadcast on NFL NETWORK.
Sunday, August 29, 2021 · Levi's® Stadium
Game Details
- Venue
- Levi's® Stadium
- Location
- Santa Clara
- Time
- 4:00 PM EDT
- Attendance
- 60,873
- Weather
- Temp: 81° F, Humidity: 56%, Wind: n/nw 6 mph
Score by Quarter
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| Las Vegas Raiders | 0 | 3 | 7 | 0 | 10 |
| San Francisco 49ers | 7 | 13 | 14 | 0 | 34 |
Broadcast
- Local TV:
- NFL NETWORK
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The San Francisco 49ers hosted the Las Vegas Raiders at Levi's® Stadium in Santa Clara on Sunday, August 29, 2021. The final score was San Francisco 49ers 34, Las Vegas Raiders 10. This was a Preseason Week 3 game. The game was broadcast on NFL NETWORK.
Sunday, September 12, 2021 · Ford Field
Game Details
- Venue
- Ford Field
- Location
- Detroit
- Time
- 1:00 PM EDT
- Attendance
- 59,374
- Weather
- Controlled Climate Temp: 68° F, Humidity: 70%, Wind: mph
Score by Quarter
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| San Francisco 49ers | 7 | 24 | 7 | 3 | 41 |
| Detroit Lions | 0 | 10 | 7 | 16 | 33 |
Broadcast
- Local TV:
- FOX
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The Detroit Lions hosted the San Francisco 49ers at Ford Field in Detroit on Sunday, September 12, 2021. The final score was Detroit Lions 33, San Francisco 49ers 41. This was a Regular Season Week 1 game. The game was broadcast on FOX.
Sunday, September 19, 2021 · Lincoln Financial Field
Game Details
- Venue
- Lincoln Financial Field
- Location
- Philadelphia
- Time
- 1:00 PM EDT
- Attendance
- 69,796
- Weather
- Clear Temp: 75° F, Humidity: 50%, Wind: N 8 mph
Score by Quarter
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| San Francisco 49ers | 0 | 7 | 0 | 10 | 17 |
| Philadelphia Eagles | 3 | 0 | 0 | 8 | 11 |
Broadcast
- Local TV:
- FOX
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The Philadelphia Eagles hosted the San Francisco 49ers at Lincoln Financial Field in Philadelphia on Sunday, September 19, 2021. The final score was Philadelphia Eagles 11, San Francisco 49ers 17. This was a Regular Season Week 2 game. The game was broadcast on FOX.
Sunday, September 26, 2021 · Levi's® Stadium
Game Details
- Venue
- Levi's® Stadium
- Location
- Santa Clara
- Time
- 8:20 PM EDT
- Attendance
- 69,853
- Weather
- Scattered clouds Temp: 69° F, Humidity: 57%, Wind: NNW 15 mph
Score by Quarter
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| Green Bay Packers | 10 | 7 | 0 | 13 | 30 |
| San Francisco 49ers | 0 | 7 | 7 | 14 | 28 |
Broadcast
- National TV:
- NBC
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The San Francisco 49ers hosted the Green Bay Packers at Levi's® Stadium in Santa Clara on Sunday, September 26, 2021. The final score was San Francisco 49ers 28, Green Bay Packers 30. This was a Regular Season Week 3 game. The game was broadcast on NBC. This is meeting 1 of 2 between the San Francisco 49ers and Green Bay Packers this season, and the San Francisco 49ers are even in the season series 1-1.
Sunday, October 3, 2021 · Levi's® Stadium
Game Details
- Venue
- Levi's® Stadium
- Location
- Santa Clara
- Time
- 4:05 PM EDT
- Attendance
- 68,912
- Weather
- Hazy skies Temp: 88° F, Humidity: 28%, Wind: nw 10 mph
Score by Quarter
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| Seattle Seahawks | 0 | 7 | 14 | 7 | 28 |
| San Francisco 49ers | 7 | 0 | 6 | 8 | 21 |
Broadcast
- Local TV:
- FOX
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The San Francisco 49ers hosted the Seattle Seahawks at Levi's® Stadium in Santa Clara on Sunday, October 3, 2021. The final score was San Francisco 49ers 21, Seattle Seahawks 28. This was a Regular Season Week 4 game. The game was broadcast on FOX. This is meeting 1 of 2 between the San Francisco 49ers and Seattle Seahawks this season, and the San Francisco 49ers trail in the season series 0-2.
Sunday, October 10, 2021 · State Farm Stadium
Game Details
- Venue
- State Farm Stadium
- Location
- Glendale
- Time
- 4:25 PM EDT
- Attendance
- 62,716
- Weather
- N/A Temp: Humidity: Wind: mph
Score by Quarter
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| San Francisco 49ers | 0 | 0 | 7 | 3 | 10 |
| Arizona Cardinals | 7 | 3 | 0 | 7 | 17 |
Broadcast
- Local TV:
- FOX
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The Arizona Cardinals hosted the San Francisco 49ers at State Farm Stadium in Glendale on Sunday, October 10, 2021. The final score was Arizona Cardinals 17, San Francisco 49ers 10. This was a Regular Season Week 5 game. The game was broadcast on FOX. This is meeting 1 of 2 between the Arizona Cardinals and San Francisco 49ers this season, and the San Francisco 49ers trail in the season series 0-2.
Sunday, October 24, 2021 · Levi's® Stadium
Game Details
- Venue
- Levi's® Stadium
- Location
- Santa Clara
- Time
- 8:20 PM EDT
- Attendance
- 56,576
- Weather
- Cloudy, rainy Temp: 64° F, Humidity: 83%, Wind: SSE 21 mph
Score by Quarter
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| Indianapolis Colts | 7 | 6 | 7 | 10 | 30 |
| San Francisco 49ers | 12 | 0 | 0 | 6 | 18 |
Broadcast
- National TV:
- NBC
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The San Francisco 49ers hosted the Indianapolis Colts at Levi's® Stadium in Santa Clara on Sunday, October 24, 2021. The final score was San Francisco 49ers 18, Indianapolis Colts 30. This was a Regular Season Week 7 game. The game was broadcast on NBC.
Sunday, October 31, 2021 · Soldier Field
Game Details
- Venue
- Soldier Field
- Location
- Chicago
- Time
- 1:00 PM EDT
- Attendance
- 60,877
- Weather
- Partly Sunny Temp: 52° F, Humidity: 69%, Wind: SE 13 mph
Score by Quarter
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| San Francisco 49ers | 3 | 6 | 6 | 18 | 33 |
| Chicago Bears | 3 | 10 | 3 | 6 | 22 |
Broadcast
- Local TV:
- FOX
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The Chicago Bears hosted the San Francisco 49ers at Soldier Field in Chicago on Sunday, October 31, 2021. The final score was Chicago Bears 22, San Francisco 49ers 33. This was a Regular Season Week 8 game. The game was broadcast on FOX.
Sunday, November 7, 2021 · Levi's® Stadium
Game Details
- Venue
- Levi's® Stadium
- Location
- Santa Clara
- Time
- 4:25 PM EST
- Attendance
- 59,012
- Weather
- scattered clouds Temp: 62° F, Humidity: 36%, Wind: nw 11 mph
Score by Quarter
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| Arizona Cardinals | 14 | 3 | 14 | 0 | 31 |
| San Francisco 49ers | 0 | 7 | 7 | 3 | 17 |
Broadcast
- Local TV:
- FOX
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The San Francisco 49ers hosted the Arizona Cardinals at Levi's® Stadium in Santa Clara on Sunday, November 7, 2021. The final score was San Francisco 49ers 17, Arizona Cardinals 31. This was a Regular Season Week 9 game. The game was broadcast on FOX. This is meeting 2 of 2 between the San Francisco 49ers and Arizona Cardinals this season, and the San Francisco 49ers trail in the season series 0-2.
Monday, November 15, 2021 · Levi's® Stadium
Game Details
- Venue
- Levi's® Stadium
- Location
- Santa Clara
- Time
- 8:15 PM EST
- Attendance
- 64,256
- Weather
- Overcast Temp: 62° F, Humidity: 71%, Wind: NW 3 mph
Score by Quarter
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| Los Angeles Rams | 0 | 7 | 0 | 3 | 10 |
| San Francisco 49ers | 14 | 7 | 3 | 7 | 31 |
Broadcast
- National TV:
- ESPN, ESPN2
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The San Francisco 49ers hosted the Los Angeles Rams at Levi's® Stadium in Santa Clara on Monday, November 15, 2021. The final score was San Francisco 49ers 31, Los Angeles Rams 10. This was a Regular Season Week 10 game. The game was broadcast on ESPN, ESPN2. This is meeting 1 of 3 between the San Francisco 49ers and Los Angeles Rams this season, and the San Francisco 49ers lead the season series 2-1.
Sunday, November 21, 2021 · EverBank Stadium
Game Details
- Venue
- EverBank Stadium
- Location
- Jacksonville
- Time
- 1:00 PM EST
- Attendance
- 60,268
- Weather
- sunny Temp: 67° F, Humidity: 82%, Wind: sw 12 mph
Score by Quarter
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| San Francisco 49ers | 3 | 17 | 7 | 3 | 30 |
| Jacksonville Jaguars | 0 | 3 | 0 | 7 | 10 |
Broadcast
- Local TV:
- FOX
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The Jacksonville Jaguars hosted the San Francisco 49ers at EverBank Stadium in Jacksonville on Sunday, November 21, 2021. The final score was Jacksonville Jaguars 10, San Francisco 49ers 30. This was a Regular Season Week 11 game. The game was broadcast on FOX.
Sunday, November 28, 2021 · Levi's® Stadium
Game Details
- Venue
- Levi's® Stadium
- Location
- Santa Clara
- Time
- 4:25 PM EST
- Attendance
- 71,493
- Weather
- Clear skies Temp: 67° F, Humidity: 49%, Wind: NW 3 mph
Score by Quarter
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| Minnesota Vikings | 7 | 7 | 12 | 0 | 26 |
| San Francisco 49ers | 7 | 7 | 20 | 0 | 34 |
Broadcast
- Local TV:
- FOX
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The San Francisco 49ers hosted the Minnesota Vikings at Levi's® Stadium in Santa Clara on Sunday, November 28, 2021. The final score was San Francisco 49ers 34, Minnesota Vikings 26. This was a Regular Season Week 12 game. The game was broadcast on FOX.
Sunday, December 5, 2021 · Lumen Field
Game Details
- Venue
- Lumen Field
- Location
- Seattle
- Time
- 4:25 PM EST
- Attendance
- 68,758
- Weather
- Sunny Temp: 41° F, Humidity: 82%, Wind: E 1 mph
Score by Quarter
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| San Francisco 49ers | 14 | 9 | 0 | 0 | 23 |
| Seattle Seahawks | 7 | 14 | 9 | 0 | 30 |
Broadcast
- Local TV:
- CBS
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The Seattle Seahawks hosted the San Francisco 49ers at Lumen Field in Seattle on Sunday, December 5, 2021. The final score was Seattle Seahawks 30, San Francisco 49ers 23. This was a Regular Season Week 13 game. The game was broadcast on CBS. This is meeting 2 of 2 between the Seattle Seahawks and San Francisco 49ers this season, and the San Francisco 49ers trail in the season series 0-2.
Sunday, December 12, 2021 · Paycor Stadium
Game Details
- Venue
- Paycor Stadium
- Location
- Cincinnati
- Time
- 4:25 PM EST
- Attendance
- 50,481
- Weather
- Sunny Temp: 45° F, Humidity: 44%, Wind: SSW 7 mph, gusts to 14 mph
Score by Quarter
| 1 | 2 | 3 | 4 | OT | T | |
|---|---|---|---|---|---|---|
| San Francisco 49ers | 3 | 14 | 3 | 0 | 6 | 26 |
| Cincinnati Bengals | 3 | 3 | 0 | 14 | 3 | 23 |
Broadcast
- Local TV:
- CBS
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The Cincinnati Bengals hosted the San Francisco 49ers at Paycor Stadium in Cincinnati on Sunday, December 12, 2021. The final score was Cincinnati Bengals 23, San Francisco 49ers 26. This was a Regular Season Week 14 game. The game was broadcast on CBS.
Sunday, December 19, 2021 · Levi's® Stadium
Game Details
- Venue
- Levi's® Stadium
- Location
- Santa Clara
- Time
- 4:05 PM EST
- Attendance
- 71,650
- Weather
- Clear Temp: 52° F, Humidity: 71%, Wind: NW 5 mph
Score by Quarter
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| Atlanta Falcons | 3 | 7 | 3 | 0 | 13 |
| San Francisco 49ers | 3 | 14 | 14 | 0 | 31 |
Broadcast
- Local TV:
- CBS
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The San Francisco 49ers hosted the Atlanta Falcons at Levi's® Stadium in Santa Clara on Sunday, December 19, 2021. The final score was San Francisco 49ers 31, Atlanta Falcons 13. This was a Regular Season Week 15 game. The game was broadcast on CBS.
Thursday, December 23, 2021 · Nissan Stadium
Game Details
- Venue
- Nissan Stadium
- Location
- Nashville
- Time
- 8:20 PM EST
- Attendance
- 69,361
- Weather
- Clear Temp: 54° F, Humidity: 33%, Wind: South 6 mph
Score by Quarter
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| San Francisco 49ers | 7 | 3 | 0 | 7 | 17 |
| Tennessee Titans | 0 | 0 | 10 | 10 | 20 |
Broadcast
- National TV:
- NFL NETWORK
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The Tennessee Titans hosted the San Francisco 49ers at Nissan Stadium in Nashville on Thursday, December 23, 2021. The final score was Tennessee Titans 20, San Francisco 49ers 17. This was a Regular Season Week 16 game. The game was broadcast on NFL NETWORK.
Sunday, January 2, 2022 · Levi's® Stadium
Game Details
- Venue
- Levi's® Stadium
- Location
- Santa Clara
- Time
- 4:05 PM EST
- Attendance
- 71,612
- Weather
- clear Temp: 64° F, Humidity: 44%, Wind: SE 5 mph
Score by Quarter
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| Houston Texans | 0 | 7 | 0 | 0 | 7 |
| San Francisco 49ers | 0 | 3 | 7 | 13 | 23 |
Broadcast
- Local TV:
- CBS
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The San Francisco 49ers hosted the Houston Texans at Levi's® Stadium in Santa Clara on Sunday, January 2, 2022. The final score was San Francisco 49ers 23, Houston Texans 7. This was a Regular Season Week 17 game. The game was broadcast on CBS.
Sunday, January 9, 2022 · SoFi Stadium
Game Details
- Venue
- SoFi Stadium
- Location
- Inglewood
- Time
- 4:25 PM EST
- Attendance
- 74,447
- Weather
- Sunny Temp: 74° F, Humidity: 20%, Wind: W 2 mph
Score by Quarter
| 1 | 2 | 3 | 4 | T | ||
|---|---|---|---|---|---|---|
| San Francisco 49ers | 0 | 3 | 14 | 7 | 3 | 27 |
| Los Angeles Rams | 3 | 14 | 0 | 7 | 24 |
Broadcast
- Local TV:
- FOX
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The Los Angeles Rams hosted the San Francisco 49ers at SoFi Stadium in Inglewood on Sunday, January 9, 2022. The final score was Los Angeles Rams 24, San Francisco 49ers 27. This was a Regular Season Week 18 game. The game was broadcast on FOX. This is meeting 2 of 3 between the Los Angeles Rams and San Francisco 49ers this season, and the San Francisco 49ers lead the season series 2-1.
Sunday, January 16, 2022 · AT&T Stadium
Game Details
- Venue
- AT&T Stadium
- Location
- Arlington
- Time
- 4:30 PM EST
- Attendance
- 93,470
Score by Quarter
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| San Francisco 49ers | 10 | 6 | 7 | 0 | 23 |
| Dallas Cowboys | 0 | 7 | 0 | 10 | 17 |
Broadcast
- National TV:
- CBS, Paramount+, NICK, Amazon Prime Video
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The Dallas Cowboys hosted the San Francisco 49ers at AT&T Stadium in Arlington on Sunday, January 16, 2022. The final score was Dallas Cowboys 17, San Francisco 49ers 23. This was a Regular Season Week 1 game. The game was broadcast on CBS, Paramount+, NICK, Amazon Prime Video.
Saturday, January 22, 2022 · Lambeau Field
Game Details
- Venue
- Lambeau Field
- Location
- Green Bay
- Time
- 8:15 PM EST
- Attendance
- 79,132
- Weather
- Cloudy Temp: 14° F, Humidity: 53%, Wind: W 13 mph
Score by Quarter
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| San Francisco 49ers | 0 | 0 | 3 | 10 | 13 |
| Green Bay Packers | 7 | 0 | 0 | 3 | 10 |
Broadcast
- National TV:
- FOX, FOX Deportes
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The Green Bay Packers hosted the San Francisco 49ers at Lambeau Field in Green Bay on Saturday, January 22, 2022. The final score was Green Bay Packers 10, San Francisco 49ers 13. This was a Regular Season Week 2 game. The game was broadcast on FOX, FOX Deportes. This is meeting 2 of 2 between the Green Bay Packers and San Francisco 49ers this season, and the San Francisco 49ers are even in the season series 1-1.
Sunday, January 30, 2022 · SoFi Stadium
Game Details
- Venue
- SoFi Stadium
- Location
- Inglewood
- Time
- 6:30 PM EST
- Attendance
- 73,202
- Weather
- Sunny Temp: 62° F, Humidity: 62%, Wind: WSW 11 mph
Score by Quarter
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| San Francisco 49ers | 0 | 10 | 7 | 0 | 17 |
| Los Angeles Rams | 0 | 7 | 0 | 13 | 20 |
Broadcast
- National TV:
- FOX
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The Los Angeles Rams hosted the San Francisco 49ers at SoFi Stadium in Inglewood on Sunday, January 30, 2022. The final score was Los Angeles Rams 20, San Francisco 49ers 17. This was a Regular Season Week 3 game. The game was broadcast on FOX. This is meeting 3 of 3 between the Los Angeles Rams and San Francisco 49ers this season, and the San Francisco 49ers lead the season series 2-1.