| Sat, Feb 22, 2025 | Houston Astros | Washington Nationals vs Houston Astros - Sat, Feb 22, 2025 | Away | CACTI Park of the Palm Beaches |
| Sun, Feb 23, 2025 | New York Mets | Washington Nationals vs New York Mets - Sun, Feb 23, 2025 | Home | CACTI Park of the Palm Beaches |
| Tue, Feb 25, 2025 | Miami Marlins | Washington Nationals vs Miami Marlins - Tue, Feb 25, 2025 | Away | Roger Dean Chevrolet Stadium |
| Wed, Feb 26, 2025 | Houston Astros | Washington Nationals vs Houston Astros - Wed, Feb 26, 2025 | Home | CACTI Park of the Palm Beaches |
| Thu, Feb 27, 2025 | Atlanta Braves | Washington Nationals vs Atlanta Braves - Thu, Feb 27, 2025 | Home | CACTI Park of the Palm Beaches |
| Fri, Feb 28, 2025 | New York Mets | Washington Nationals vs New York Mets - Fri, Feb 28, 2025 | Away | Clover Park |
| Sat, Mar 1, 2025 | St Louis Cardinals | Washington Nationals vs St Louis Cardinals - Sat, Mar 1, 2025 | Away | Roger Dean Chevrolet Stadium |
| Sat, Mar 1, 2025 | Miami Marlins | Washington Nationals vs Miami Marlins - Sat, Mar 1, 2025 | Home | CACTI Park of the Palm Beaches |
| Sun, Mar 2, 2025 | Houston Astros | Washington Nationals vs Houston Astros - Sun, Mar 2, 2025 | Away | CACTI Park of the Palm Beaches |
| Tue, Mar 4, 2025 | St Louis Cardinals | Washington Nationals vs St Louis Cardinals - Tue, Mar 4, 2025 | Home | CACTI Park of the Palm Beaches |
| Wed, Mar 5, 2025 | Miami Marlins | Washington Nationals vs Miami Marlins - Wed, Mar 5, 2025 | Away | Roger Dean Chevrolet Stadium |
| Thu, Mar 6, 2025 | St Louis Cardinals | Washington Nationals vs St Louis Cardinals - Thu, Mar 6, 2025 | Away | Roger Dean Chevrolet Stadium |
| Fri, Mar 7, 2025 | New York Mets | Washington Nationals vs New York Mets - Fri, Mar 7, 2025 | Home | CACTI Park of the Palm Beaches |
| Sat, Mar 8, 2025 | St Louis Cardinals | Washington Nationals vs St Louis Cardinals - Sat, Mar 8, 2025 | Home | CACTI Park of the Palm Beaches |
| Sun, Mar 9, 2025 | New York Mets | Washington Nationals vs New York Mets - Sun, Mar 9, 2025 | Away | Clover Park |
| Mon, Mar 10, 2025 | Miami Marlins | Washington Nationals vs Miami Marlins - Mon, Mar 10, 2025 | Away | Roger Dean Chevrolet Stadium |
| Mon, Mar 10, 2025 | Miami Marlins | Washington Nationals vs Miami Marlins - Mon, Mar 10, 2025 | Home | CACTI Park of the Palm Beaches |
| Wed, Mar 12, 2025 | Houston Astros | Washington Nationals vs Houston Astros - Wed, Mar 12, 2025 | Home | CACTI Park of the Palm Beaches |
| Thu, Mar 13, 2025 | Tampa Bay Rays | Washington Nationals vs Tampa Bay Rays - Thu, Mar 13, 2025 | Away | Charlotte Sports Park |
| Fri, Mar 14, 2025 | Atlanta Braves | Washington Nationals vs Atlanta Braves - Fri, Mar 14, 2025 | Away | CoolToday Park |
| Sat, Mar 15, 2025 | New York Mets | Washington Nationals vs New York Mets - Sat, Mar 15, 2025 | Home | CACTI Park of the Palm Beaches |
| Sun, Mar 16, 2025 | Tampa Bay Rays | Washington Nationals vs Tampa Bay Rays - Sun, Mar 16, 2025 | Home | CACTI Park of the Palm Beaches |
| Mon, Mar 17, 2025 | St Louis Cardinals | Washington Nationals vs St Louis Cardinals - Mon, Mar 17, 2025 | Home | CACTI Park of the Palm Beaches |
| Tue, Mar 18, 2025 | Houston Astros | Washington Nationals vs Houston Astros - Tue, Mar 18, 2025 | Away | CACTI Park of the Palm Beaches |
| Wed, Mar 19, 2025 | St Louis Cardinals | Washington Nationals vs St Louis Cardinals - Wed, Mar 19, 2025 | Away | Roger Dean Chevrolet Stadium |
| Thu, Mar 20, 2025 | New York Mets | Washington Nationals vs New York Mets - Thu, Mar 20, 2025 | Home | CACTI Park of the Palm Beaches |
| Fri, Mar 21, 2025 | Miami Marlins | Washington Nationals vs Miami Marlins - Fri, Mar 21, 2025 | Home | CACTI Park of the Palm Beaches |
| Sat, Mar 22, 2025 | New York Mets | Washington Nationals vs New York Mets - Sat, Mar 22, 2025 | Away | Clover Park |
| Sun, Mar 23, 2025 | Houston Astros | Washington Nationals vs Houston Astros - Sun, Mar 23, 2025 | Home | CACTI Park of the Palm Beaches |
| Sun, Mar 23, 2025 | St Louis Cardinals | Washington Nationals vs St Louis Cardinals - Sun, Mar 23, 2025 | Away | Roger Dean Chevrolet Stadium |
| Mon, Mar 24, 2025 | Baltimore Orioles | Washington Nationals vs Baltimore Orioles - Mon, Mar 24, 2025 | Home | Nationals Park |
| Thu, Mar 27, 2025 | Philadelphia Phillies | Washington Nationals vs Philadelphia Phillies - Thu, Mar 27, 2025 | Home | Nationals Park |
| Sat, Mar 29, 2025 | Philadelphia Phillies | Washington Nationals vs Philadelphia Phillies - Sat, Mar 29, 2025 | Home | Nationals Park |
| Sun, Mar 30, 2025 | Philadelphia Phillies | Washington Nationals vs Philadelphia Phillies - Sun, Mar 30, 2025 | Home | Nationals Park |
| Mon, Mar 31, 2025 | Toronto Blue Jays | Washington Nationals vs Toronto Blue Jays - Mon, Mar 31, 2025 | Away | Rogers Centre |
| Tue, Apr 1, 2025 | Toronto Blue Jays | Washington Nationals vs Toronto Blue Jays - Tue, Apr 1, 2025 | Away | Rogers Centre |
| Wed, Apr 2, 2025 | Toronto Blue Jays | Washington Nationals vs Toronto Blue Jays - Wed, Apr 2, 2025 | Away | Rogers Centre |
| Fri, Apr 4, 2025 | Arizona Diamondbacks | Washington Nationals vs Arizona Diamondbacks - Fri, Apr 4, 2025 | Home | Nationals Park |
| Sat, Apr 5, 2025 | Arizona Diamondbacks | Washington Nationals vs Arizona Diamondbacks - Sat, Apr 5, 2025 | Home | Nationals Park |
| Sun, Apr 6, 2025 | Arizona Diamondbacks | Washington Nationals vs Arizona Diamondbacks - Sun, Apr 6, 2025 | Home | Nationals Park |
| Mon, Apr 7, 2025 | Los Angeles Dodgers | Washington Nationals vs Los Angeles Dodgers - Mon, Apr 7, 2025 | Home | Nationals Park |
| Tue, Apr 8, 2025 | Los Angeles Dodgers | Washington Nationals vs Los Angeles Dodgers - Tue, Apr 8, 2025 | Home | Nationals Park |
| Wed, Apr 9, 2025 | Los Angeles Dodgers | Washington Nationals vs Los Angeles Dodgers - Wed, Apr 9, 2025 | Home | Nationals Park |
| Fri, Apr 11, 2025 | Miami Marlins | Washington Nationals vs Miami Marlins - Fri, Apr 11, 2025 | Away | loanDepot park |
| Sat, Apr 12, 2025 | Miami Marlins | Washington Nationals vs Miami Marlins - Sat, Apr 12, 2025 | Away | loanDepot park |
| Sun, Apr 13, 2025 | Miami Marlins | Washington Nationals vs Miami Marlins - Sun, Apr 13, 2025 | Away | loanDepot park |
| Mon, Apr 14, 2025 | Pittsburgh Pirates | Washington Nationals vs Pittsburgh Pirates - Mon, Apr 14, 2025 | Away | PNC Park |
| Tue, Apr 15, 2025 | Pittsburgh Pirates | Washington Nationals vs Pittsburgh Pirates - Tue, Apr 15, 2025 | Away | PNC Park |
| Wed, Apr 16, 2025 | Pittsburgh Pirates | Washington Nationals vs Pittsburgh Pirates - Wed, Apr 16, 2025 | Away | PNC Park |
| Thu, Apr 17, 2025 | Pittsburgh Pirates | Washington Nationals vs Pittsburgh Pirates - Thu, Apr 17, 2025 | Away | PNC Park |
| Sat, Apr 19, 2025 | Colorado Rockies | Washington Nationals vs Colorado Rockies - Sat, Apr 19, 2025 | Away | Coors Field |
| Sun, Apr 20, 2025 | Colorado Rockies | Washington Nationals vs Colorado Rockies - Sun, Apr 20, 2025 | Away | Coors Field |
| Sun, Apr 20, 2025 | Colorado Rockies | Washington Nationals vs Colorado Rockies - Sun, Apr 20, 2025 | Away | Coors Field |
| Tue, Apr 22, 2025 | Baltimore Orioles | Washington Nationals vs Baltimore Orioles - Tue, Apr 22, 2025 | Home | Nationals Park |
| Wed, Apr 23, 2025 | Baltimore Orioles | Washington Nationals vs Baltimore Orioles - Wed, Apr 23, 2025 | Home | Nationals Park |
| Thu, Apr 24, 2025 | Baltimore Orioles | Washington Nationals vs Baltimore Orioles - Thu, Apr 24, 2025 | Home | Nationals Park |
| Fri, Apr 25, 2025 | New York Mets | Washington Nationals vs New York Mets - Fri, Apr 25, 2025 | Home | Nationals Park |
| Sat, Apr 26, 2025 | New York Mets | Washington Nationals vs New York Mets - Sat, Apr 26, 2025 | Home | Nationals Park |
| Sun, Apr 27, 2025 | New York Mets | Washington Nationals vs New York Mets - Sun, Apr 27, 2025 | Home | Nationals Park |
| Mon, Apr 28, 2025 | New York Mets | Washington Nationals vs New York Mets - Mon, Apr 28, 2025 | Home | Nationals Park |
| Tue, Apr 29, 2025 | Philadelphia Phillies | Washington Nationals vs Philadelphia Phillies - Tue, Apr 29, 2025 | Away | Citizens Bank Park |
| Wed, Apr 30, 2025 | Philadelphia Phillies | Washington Nationals vs Philadelphia Phillies - Wed, Apr 30, 2025 | Away | Citizens Bank Park |
| Thu, May 1, 2025 | Philadelphia Phillies | Washington Nationals vs Philadelphia Phillies - Thu, May 1, 2025 | Away | Citizens Bank Park |
| Fri, May 2, 2025 | Cincinnati Reds | Washington Nationals vs Cincinnati Reds - Fri, May 2, 2025 | Away | Great American Ball Park |
| Sat, May 3, 2025 | Cincinnati Reds | Washington Nationals vs Cincinnati Reds - Sat, May 3, 2025 | Away | Great American Ball Park |
| Sun, May 4, 2025 | Cincinnati Reds | Washington Nationals vs Cincinnati Reds - Sun, May 4, 2025 | Away | Great American Ball Park |
| Tue, May 6, 2025 | Cleveland Guardians | Washington Nationals vs Cleveland Guardians - Tue, May 6, 2025 | Home | Nationals Park |
| Tue, May 6, 2025 | Cleveland Guardians | Washington Nationals vs Cleveland Guardians - Tue, May 6, 2025 | Home | Nationals Park |
| Wed, May 7, 2025 | Cleveland Guardians | Washington Nationals vs Cleveland Guardians - Wed, May 7, 2025 | Home | Nationals Park |
| Fri, May 9, 2025 | St Louis Cardinals | Washington Nationals vs St Louis Cardinals - Fri, May 9, 2025 | Home | Nationals Park |
| Sat, May 10, 2025 | St Louis Cardinals | Washington Nationals vs St Louis Cardinals - Sat, May 10, 2025 | Home | Nationals Park |
| Sun, May 11, 2025 | St Louis Cardinals | Washington Nationals vs St Louis Cardinals - Sun, May 11, 2025 | Home | Nationals Park |
| Mon, May 12, 2025 | Atlanta Braves | Washington Nationals vs Atlanta Braves - Mon, May 12, 2025 | Away | Truist Park |
| Tue, May 13, 2025 | Atlanta Braves | Washington Nationals vs Atlanta Braves - Tue, May 13, 2025 | Away | Truist Park |
| Wed, May 14, 2025 | Atlanta Braves | Washington Nationals vs Atlanta Braves - Wed, May 14, 2025 | Away | Truist Park |
| Thu, May 15, 2025 | Atlanta Braves | Washington Nationals vs Atlanta Braves - Thu, May 15, 2025 | Away | Truist Park |
| Fri, May 16, 2025 | Baltimore Orioles | Washington Nationals vs Baltimore Orioles - Fri, May 16, 2025 | Away | Oriole Park at Camden Yards |
| Sat, May 17, 2025 | Baltimore Orioles | Washington Nationals vs Baltimore Orioles - Sat, May 17, 2025 | Away | Oriole Park at Camden Yards |
| Sun, May 18, 2025 | Baltimore Orioles | Washington Nationals vs Baltimore Orioles - Sun, May 18, 2025 | Away | Oriole Park at Camden Yards |
| Tue, May 20, 2025 | Atlanta Braves | Washington Nationals vs Atlanta Braves - Tue, May 20, 2025 | Home | Nationals Park |
| Thu, May 22, 2025 | Atlanta Braves | Washington Nationals vs Atlanta Braves - Thu, May 22, 2025 | Home | Nationals Park |
| Fri, May 23, 2025 | San Francisco Giants | Washington Nationals vs San Francisco Giants - Fri, May 23, 2025 | Home | Nationals Park |
| Sat, May 24, 2025 | San Francisco Giants | Washington Nationals vs San Francisco Giants - Sat, May 24, 2025 | Home | Nationals Park |
| Sun, May 25, 2025 | San Francisco Giants | Washington Nationals vs San Francisco Giants - Sun, May 25, 2025 | Home | Nationals Park |
| Tue, May 27, 2025 | Seattle Mariners | Washington Nationals vs Seattle Mariners - Tue, May 27, 2025 | Away | T-Mobile Park |
| Wed, May 28, 2025 | Seattle Mariners | Washington Nationals vs Seattle Mariners - Wed, May 28, 2025 | Away | T-Mobile Park |
| Thu, May 29, 2025 | Seattle Mariners | Washington Nationals vs Seattle Mariners - Thu, May 29, 2025 | Away | T-Mobile Park |
| Fri, May 30, 2025 | Arizona Diamondbacks | Washington Nationals vs Arizona Diamondbacks - Fri, May 30, 2025 | Away | Chase Field |
| Sat, May 31, 2025 | Arizona Diamondbacks | Washington Nationals vs Arizona Diamondbacks - Sat, May 31, 2025 | Away | Chase Field |
| Sun, Jun 1, 2025 | Arizona Diamondbacks | Washington Nationals vs Arizona Diamondbacks - Sun, Jun 1, 2025 | Away | Chase Field |
| Tue, Jun 3, 2025 | Chicago Cubs | Washington Nationals vs Chicago Cubs - Tue, Jun 3, 2025 | Home | Nationals Park |
| Wed, Jun 4, 2025 | Chicago Cubs | Washington Nationals vs Chicago Cubs - Wed, Jun 4, 2025 | Home | Nationals Park |
| Thu, Jun 5, 2025 | Chicago Cubs | Washington Nationals vs Chicago Cubs - Thu, Jun 5, 2025 | Home | Nationals Park |
| Fri, Jun 6, 2025 | Texas Rangers | Washington Nationals vs Texas Rangers - Fri, Jun 6, 2025 | Home | Nationals Park |
| Sat, Jun 7, 2025 | Texas Rangers | Washington Nationals vs Texas Rangers - Sat, Jun 7, 2025 | Home | Nationals Park |
| Sun, Jun 8, 2025 | Texas Rangers | Washington Nationals vs Texas Rangers - Sun, Jun 8, 2025 | Home | Nationals Park |
| Tue, Jun 10, 2025 | New York Mets | Washington Nationals vs New York Mets - Tue, Jun 10, 2025 | Away | Citi Field |
| Wed, Jun 11, 2025 | New York Mets | Washington Nationals vs New York Mets - Wed, Jun 11, 2025 | Away | Citi Field |
| Thu, Jun 12, 2025 | New York Mets | Washington Nationals vs New York Mets - Thu, Jun 12, 2025 | Away | Citi Field |
| Fri, Jun 13, 2025 | Miami Marlins | Washington Nationals vs Miami Marlins - Fri, Jun 13, 2025 | Home | Nationals Park |
| Sat, Jun 14, 2025 | Miami Marlins | Washington Nationals vs Miami Marlins - Sat, Jun 14, 2025 | Home | Nationals Park |
| Sun, Jun 15, 2025 | Miami Marlins | Washington Nationals vs Miami Marlins - Sun, Jun 15, 2025 | Home | Nationals Park |
| Mon, Jun 16, 2025 | Colorado Rockies | Washington Nationals vs Colorado Rockies - Mon, Jun 16, 2025 | Home | Nationals Park |
| Tue, Jun 17, 2025 | Colorado Rockies | Washington Nationals vs Colorado Rockies - Tue, Jun 17, 2025 | Home | Nationals Park |
| Wed, Jun 18, 2025 | Colorado Rockies | Washington Nationals vs Colorado Rockies - Wed, Jun 18, 2025 | Home | Nationals Park |
| Thu, Jun 19, 2025 | Colorado Rockies | Washington Nationals vs Colorado Rockies - Thu, Jun 19, 2025 | Home | Nationals Park |
| Fri, Jun 20, 2025 | Los Angeles Dodgers | Washington Nationals vs Los Angeles Dodgers - Fri, Jun 20, 2025 | Away | Dodger Stadium |
| Sat, Jun 21, 2025 | Los Angeles Dodgers | Washington Nationals vs Los Angeles Dodgers - Sat, Jun 21, 2025 | Away | Dodger Stadium |
| Sun, Jun 22, 2025 | Los Angeles Dodgers | Washington Nationals vs Los Angeles Dodgers - Sun, Jun 22, 2025 | Away | Dodger Stadium |
| Mon, Jun 23, 2025 | San Diego Padres | Washington Nationals vs San Diego Padres - Mon, Jun 23, 2025 | Away | Petco Park |
| Tue, Jun 24, 2025 | San Diego Padres | Washington Nationals vs San Diego Padres - Tue, Jun 24, 2025 | Away | Petco Park |
| Wed, Jun 25, 2025 | San Diego Padres | Washington Nationals vs San Diego Padres - Wed, Jun 25, 2025 | Away | Petco Park |
| Fri, Jun 27, 2025 | Los Angeles Angels | Washington Nationals vs Los Angeles Angels - Fri, Jun 27, 2025 | Away | Angel Stadium |
| Sat, Jun 28, 2025 | Los Angeles Angels | Washington Nationals vs Los Angeles Angels - Sat, Jun 28, 2025 | Away | Angel Stadium |
| Sun, Jun 29, 2025 | Los Angeles Angels | Washington Nationals vs Los Angeles Angels - Sun, Jun 29, 2025 | Away | Angel Stadium |
| Wed, Jul 2, 2025 | Detroit Tigers | Washington Nationals vs Detroit Tigers - Wed, Jul 2, 2025 | Home | Nationals Park |
| Wed, Jul 2, 2025 | Detroit Tigers | Washington Nationals vs Detroit Tigers - Wed, Jul 2, 2025 | Home | Nationals Park |
| Thu, Jul 3, 2025 | Detroit Tigers | Washington Nationals vs Detroit Tigers - Thu, Jul 3, 2025 | Home | Nationals Park |
| Fri, Jul 4, 2025 | Boston Red Sox | Washington Nationals vs Boston Red Sox - Fri, Jul 4, 2025 | Home | Nationals Park |
| Sat, Jul 5, 2025 | Boston Red Sox | Washington Nationals vs Boston Red Sox - Sat, Jul 5, 2025 | Home | Nationals Park |
| Sun, Jul 6, 2025 | Boston Red Sox | Washington Nationals vs Boston Red Sox - Sun, Jul 6, 2025 | Home | Nationals Park |
| Tue, Jul 8, 2025 | St Louis Cardinals | Washington Nationals vs St Louis Cardinals - Tue, Jul 8, 2025 | Away | Busch Stadium |
| Wed, Jul 9, 2025 | St Louis Cardinals | Washington Nationals vs St Louis Cardinals - Wed, Jul 9, 2025 | Away | Busch Stadium |
| Thu, Jul 10, 2025 | St Louis Cardinals | Washington Nationals vs St Louis Cardinals - Thu, Jul 10, 2025 | Away | Busch Stadium |
| Fri, Jul 11, 2025 | Milwaukee Brewers | Washington Nationals vs Milwaukee Brewers - Fri, Jul 11, 2025 | Away | American Family Field |
| Sat, Jul 12, 2025 | Milwaukee Brewers | Washington Nationals vs Milwaukee Brewers - Sat, Jul 12, 2025 | Away | American Family Field |
| Sun, Jul 13, 2025 | Milwaukee Brewers | Washington Nationals vs Milwaukee Brewers - Sun, Jul 13, 2025 | Away | American Family Field |
| Fri, Jul 18, 2025 | San Diego Padres | Washington Nationals vs San Diego Padres - Fri, Jul 18, 2025 | Home | Nationals Park |
| Sat, Jul 19, 2025 | San Diego Padres | Washington Nationals vs San Diego Padres - Sat, Jul 19, 2025 | Home | Nationals Park |
| Sun, Jul 20, 2025 | San Diego Padres | Washington Nationals vs San Diego Padres - Sun, Jul 20, 2025 | Home | Nationals Park |
| Mon, Jul 21, 2025 | Cincinnati Reds | Washington Nationals vs Cincinnati Reds - Mon, Jul 21, 2025 | Home | Nationals Park |
| Tue, Jul 22, 2025 | Cincinnati Reds | Washington Nationals vs Cincinnati Reds - Tue, Jul 22, 2025 | Home | Nationals Park |
| Wed, Jul 23, 2025 | Cincinnati Reds | Washington Nationals vs Cincinnati Reds - Wed, Jul 23, 2025 | Home | Nationals Park |
| Fri, Jul 25, 2025 | Minnesota Twins | Washington Nationals vs Minnesota Twins - Fri, Jul 25, 2025 | Away | Target Field |
| Sat, Jul 26, 2025 | Minnesota Twins | Washington Nationals vs Minnesota Twins - Sat, Jul 26, 2025 | Away | Target Field |
| Sun, Jul 27, 2025 | Minnesota Twins | Washington Nationals vs Minnesota Twins - Sun, Jul 27, 2025 | Away | Target Field |
| Mon, Jul 28, 2025 | Houston Astros | Washington Nationals vs Houston Astros - Mon, Jul 28, 2025 | Away | Daikin Park |
| Tue, Jul 29, 2025 | Houston Astros | Washington Nationals vs Houston Astros - Tue, Jul 29, 2025 | Away | Daikin Park |
| Wed, Jul 30, 2025 | Houston Astros | Washington Nationals vs Houston Astros - Wed, Jul 30, 2025 | Away | Daikin Park |
| Fri, Aug 1, 2025 | Milwaukee Brewers | Washington Nationals vs Milwaukee Brewers - Fri, Aug 1, 2025 | Home | Nationals Park |
| Sat, Aug 2, 2025 | Milwaukee Brewers | Washington Nationals vs Milwaukee Brewers - Sat, Aug 2, 2025 | Home | Nationals Park |
| Sun, Aug 3, 2025 | Milwaukee Brewers | Washington Nationals vs Milwaukee Brewers - Sun, Aug 3, 2025 | Home | Nationals Park |
| Tue, Aug 5, 2025 | Oakland Athletics | Washington Nationals vs Oakland Athletics - Tue, Aug 5, 2025 | Home | Nationals Park |
| Wed, Aug 6, 2025 | Oakland Athletics | Washington Nationals vs Oakland Athletics - Wed, Aug 6, 2025 | Home | Nationals Park |
| Thu, Aug 7, 2025 | Oakland Athletics | Washington Nationals vs Oakland Athletics - Thu, Aug 7, 2025 | Home | Nationals Park |
| Fri, Aug 8, 2025 | San Francisco Giants | Washington Nationals vs San Francisco Giants - Fri, Aug 8, 2025 | Away | Oracle Park |
| Sat, Aug 9, 2025 | San Francisco Giants | Washington Nationals vs San Francisco Giants - Sat, Aug 9, 2025 | Away | Oracle Park |
| Sun, Aug 10, 2025 | San Francisco Giants | Washington Nationals vs San Francisco Giants - Sun, Aug 10, 2025 | Away | Oracle Park |
| Mon, Aug 11, 2025 | Kansas City Royals | Washington Nationals vs Kansas City Royals - Mon, Aug 11, 2025 | Away | Kauffman Stadium |
| Tue, Aug 12, 2025 | Kansas City Royals | Washington Nationals vs Kansas City Royals - Tue, Aug 12, 2025 | Away | Kauffman Stadium |
| Wed, Aug 13, 2025 | Kansas City Royals | Washington Nationals vs Kansas City Royals - Wed, Aug 13, 2025 | Away | Kauffman Stadium |
| Thu, Aug 14, 2025 | Philadelphia Phillies | Washington Nationals vs Philadelphia Phillies - Thu, Aug 14, 2025 | Home | Nationals Park |
| Fri, Aug 15, 2025 | Philadelphia Phillies | Washington Nationals vs Philadelphia Phillies - Fri, Aug 15, 2025 | Home | Nationals Park |
| Sat, Aug 16, 2025 | Philadelphia Phillies | Washington Nationals vs Philadelphia Phillies - Sat, Aug 16, 2025 | Home | Nationals Park |
| Sun, Aug 17, 2025 | Philadelphia Phillies | Washington Nationals vs Philadelphia Phillies - Sun, Aug 17, 2025 | Home | Nationals Park |
| Tue, Aug 19, 2025 | New York Mets | Washington Nationals vs New York Mets - Tue, Aug 19, 2025 | Home | Nationals Park |
| Wed, Aug 20, 2025 | New York Mets | Washington Nationals vs New York Mets - Wed, Aug 20, 2025 | Home | Nationals Park |
| Thu, Aug 21, 2025 | New York Mets | Washington Nationals vs New York Mets - Thu, Aug 21, 2025 | Home | Nationals Park |
| Fri, Aug 22, 2025 | Philadelphia Phillies | Washington Nationals vs Philadelphia Phillies - Fri, Aug 22, 2025 | Away | Citizens Bank Park |
| Sat, Aug 23, 2025 | Philadelphia Phillies | Washington Nationals vs Philadelphia Phillies - Sat, Aug 23, 2025 | Away | Citizens Bank Park |
| Sun, Aug 24, 2025 | Philadelphia Phillies | Washington Nationals vs Philadelphia Phillies - Sun, Aug 24, 2025 | Away | Citizens Bank Park |
| Mon, Aug 25, 2025 | New York Yankees | Washington Nationals vs New York Yankees - Mon, Aug 25, 2025 | Away | Yankee Stadium |
| Tue, Aug 26, 2025 | New York Yankees | Washington Nationals vs New York Yankees - Tue, Aug 26, 2025 | Away | Yankee Stadium |
| Wed, Aug 27, 2025 | New York Yankees | Washington Nationals vs New York Yankees - Wed, Aug 27, 2025 | Away | Yankee Stadium |
| Fri, Aug 29, 2025 | Tampa Bay Rays | Washington Nationals vs Tampa Bay Rays - Fri, Aug 29, 2025 | Home | Nationals Park |
| Sat, Aug 30, 2025 | Tampa Bay Rays | Washington Nationals vs Tampa Bay Rays - Sat, Aug 30, 2025 | Home | Nationals Park |
| Sun, Aug 31, 2025 | Tampa Bay Rays | Washington Nationals vs Tampa Bay Rays - Sun, Aug 31, 2025 | Home | Nationals Park |
| Mon, Sep 1, 2025 | Miami Marlins | Washington Nationals vs Miami Marlins - Mon, Sep 1, 2025 | Home | Nationals Park |
| Tue, Sep 2, 2025 | Miami Marlins | Washington Nationals vs Miami Marlins - Tue, Sep 2, 2025 | Home | Nationals Park |
| Wed, Sep 3, 2025 | Miami Marlins | Washington Nationals vs Miami Marlins - Wed, Sep 3, 2025 | Home | Nationals Park |
| Fri, Sep 5, 2025 | Chicago Cubs | Washington Nationals vs Chicago Cubs - Fri, Sep 5, 2025 | Away | Wrigley Field |
| Sat, Sep 6, 2025 | Chicago Cubs | Washington Nationals vs Chicago Cubs - Sat, Sep 6, 2025 | Away | Wrigley Field |
| Sun, Sep 7, 2025 | Chicago Cubs | Washington Nationals vs Chicago Cubs - Sun, Sep 7, 2025 | Away | Wrigley Field |
| Mon, Sep 8, 2025 | Miami Marlins | Washington Nationals vs Miami Marlins - Mon, Sep 8, 2025 | Away | loanDepot park |
| Tue, Sep 9, 2025 | Miami Marlins | Washington Nationals vs Miami Marlins - Tue, Sep 9, 2025 | Away | loanDepot park |
| Wed, Sep 10, 2025 | Miami Marlins | Washington Nationals vs Miami Marlins - Wed, Sep 10, 2025 | Away | loanDepot park |
| Thu, Sep 11, 2025 | Miami Marlins | Washington Nationals vs Miami Marlins - Thu, Sep 11, 2025 | Away | loanDepot park |
| Fri, Sep 12, 2025 | Pittsburgh Pirates | Washington Nationals vs Pittsburgh Pirates - Fri, Sep 12, 2025 | Home | Nationals Park |
| Sat, Sep 13, 2025 | Pittsburgh Pirates | Washington Nationals vs Pittsburgh Pirates - Sat, Sep 13, 2025 | Home | Nationals Park |
| Sun, Sep 14, 2025 | Pittsburgh Pirates | Washington Nationals vs Pittsburgh Pirates - Sun, Sep 14, 2025 | Home | Nationals Park |
| Mon, Sep 15, 2025 | Atlanta Braves | Washington Nationals vs Atlanta Braves - Mon, Sep 15, 2025 | Home | Nationals Park |
| Tue, Sep 16, 2025 | Atlanta Braves | Washington Nationals vs Atlanta Braves - Tue, Sep 16, 2025 | Home | Nationals Park |
| Tue, Sep 16, 2025 | Atlanta Braves | Washington Nationals vs Atlanta Braves - Tue, Sep 16, 2025 | Home | Nationals Park |
| Wed, Sep 17, 2025 | Atlanta Braves | Washington Nationals vs Atlanta Braves - Wed, Sep 17, 2025 | Home | Nationals Park |
| Fri, Sep 19, 2025 | New York Mets | Washington Nationals vs New York Mets - Fri, Sep 19, 2025 | Away | Citi Field |
| Sat, Sep 20, 2025 | New York Mets | Washington Nationals vs New York Mets - Sat, Sep 20, 2025 | Away | Citi Field |
| Sun, Sep 21, 2025 | New York Mets | Washington Nationals vs New York Mets - Sun, Sep 21, 2025 | Away | Citi Field |
| Mon, Sep 22, 2025 | Atlanta Braves | Washington Nationals vs Atlanta Braves - Mon, Sep 22, 2025 | Away | Truist Park |
| Tue, Sep 23, 2025 | Atlanta Braves | Washington Nationals vs Atlanta Braves - Tue, Sep 23, 2025 | Away | Truist Park |
| Wed, Sep 24, 2025 | Atlanta Braves | Washington Nationals vs Atlanta Braves - Wed, Sep 24, 2025 | Away | Truist Park |
| Fri, Sep 26, 2025 | Chicago White Sox | Washington Nationals vs Chicago White Sox - Fri, Sep 26, 2025 | Home | Nationals Park |
| Sat, Sep 27, 2025 | Chicago White Sox | Washington Nationals vs Chicago White Sox - Sat, Sep 27, 2025 | Home | Nationals Park |
| Sun, Sep 28, 2025 | Chicago White Sox | Washington Nationals vs Chicago White Sox - Sun, Sep 28, 2025 | Home | Nationals Park |
